媽媽育兒網(wǎng)
當(dāng)前位置: 主頁(yè) > 懷孕 > 注意 >

卵巢癌的早起診斷與普查預(yù)防方法

出處：網(wǎng)絡(luò)收集 日期：2024-07-02 09:51:10 編輯：秩名

1卵巢癌知多少？

 
卵巢癌是比較常見(jiàn)的女性生殖道惡性腫瘤。由于早期診斷率低下，絕大多數(shù)患者確診時(shí)已屬晚期，加之目前總的5年生存率低下，因此，卵巢癌雖然在發(fā)病率上僅占女性生殖器官的第3位，但導(dǎo)致的死亡，占生殖道惡性腫瘤的第1位；我國(guó)婦女死于卵巢癌的，占惡性腫瘤的第7位。估計(jì)每年有數(shù)以萬(wàn)計(jì)的婦女因患卵巢癌而死亡，數(shù)量上永遠(yuǎn)多于宮頸癌。
 

2如何早期診斷？

 
卵巢是個(gè)很小的器官，輸卵管更小。一旦發(fā)生腫瘤，早期幾乎沒(méi)有什么癥狀。即使是到了晚期，也只是有些腹脹、胃口不好、吃不下飯、消化不良之類(lèi)的非特異性癥狀，等有了腹水和腫塊等癥狀和體征，一般也就到了晚期。
 
一旦發(fā)生了卵巢腫瘤，應(yīng)該進(jìn)行盆腔超聲診斷和血CA 125、HE4 和CA199等腫瘤標(biāo)記物的檢查，必要時(shí)還要進(jìn)行CT或MR檢 查，才能確診。不過(guò)晚期卵巢腫瘤中，經(jīng)醫(yī)生用手診斷出的腫瘤，陽(yáng)性率也不低。因?yàn)橥砥诼殉材[瘤多數(shù)伴有盆腔內(nèi)轉(zhuǎn)移，尤其是有腹水和子宮直腸窩的轉(zhuǎn)移灶，這兩個(gè)體征使用三合診和肛門(mén)指診，對(duì)判斷病情是否還可以手術(shù)價(jià)值，非常重要。腹水可以經(jīng)過(guò)叩診確定，而盆腔內(nèi)的轉(zhuǎn)移灶，對(duì)醫(yī)生判斷手術(shù)時(shí)是否可以完全切下 來(lái)，是影像學(xué)檢查無(wú)法解決的。由于很多卵巢癌患者都是首先收在內(nèi)科、外科等科室，如果這些科室的醫(yī)生習(xí)慣于給患者做肛門(mén)指檢，很多患者還是有手術(shù)機(jī)會(huì)的。
 

3 有何普查方法？    

 
很多人將超聲檢查和卵巢癌的腫瘤標(biāo)記物如CA125、HE4值結(jié)合起來(lái)，用于卵巢癌的普查，但這些辦法無(wú)論是從經(jīng)濟(jì)上還是從普查的效率上考慮，都無(wú)法將早期卵巢癌檢查出來(lái)。目前沒(méi)有公認(rèn)的、好的辦法進(jìn)行卵巢癌的普查。
 

4   為什么切除輸卵管可與預(yù)防卵巢癌？

 
卵巢腫瘤的分類(lèi)十分復(fù)雜。我們這里談?wù)摰穆殉舶?，?shí)際上是指卵巢的上皮癌，大約占卵巢惡性腫瘤的80%以上。其中，漿液性卵巢癌又占上皮性卵巢癌的絕大多數(shù)。研究發(fā)現(xiàn)卵巢上皮性癌中的癌細(xì)胞來(lái)自于輸卵管傘端上皮細(xì)胞突變?，F(xiàn)在越來(lái)越多的證據(jù)表明，卵巢癌與輸卵管上皮細(xì)胞的突變有關(guān)。因此，切除攜帶有這類(lèi)基因的人的輸卵管，從理論上講是具有預(yù)防卵巢癌的作用的，但目前尚沒(méi)有大規(guī)模的、前瞻性的研究支持。
 

5  卵巢癌會(huì)遺傳嗎？

 
 卵巢癌不會(huì)異常，但攜帶有BRCA1基因的人，容易罹患乳腺癌和卵巢癌。遺傳的是容易患癌癥的易感基因，而不是直接遺傳了癌癥。目前發(fā)現(xiàn)有很多類(lèi)型的癌基因與卵巢癌有關(guān)， BRCA1/2只是其中較常見(jiàn)的，大約10-25%的乳腺癌和卵巢癌與之有關(guān)。這種人很容易患乳腺癌、卵巢癌、輸卵管癌和原發(fā)性腹膜癌，其患病幾率高達(dá)70%， 所以對(duì)這類(lèi)高危家族的人，可以在知情的前提下，可以接受患者要求行輸卵管切除的請(qǐng)求。
 
盡管如此，一般不主張切除乳腺，因?yàn)槿橄龠@個(gè)器官位于人體的表面，早期乳腺癌是比較容易診斷出來(lái)的。應(yīng)該教會(huì)這類(lèi)人自己捫診自己的乳房，一旦發(fā)現(xiàn)有硬結(jié)或腫塊，及時(shí)到醫(yī)院檢查，以期早期發(fā)現(xiàn)乳腺癌。
 

6  對(duì)于這些容易罹患癌癥的基因，有什么地方可以檢測(cè)嗎？

 
從技術(shù)上講，檢測(cè)這些基因都不難。極少數(shù)醫(yī)療機(jī)構(gòu)從研究出發(fā)，目前已經(jīng)開(kāi)展了這方面的研究，但是尚未推出面向公眾的癌基因檢測(cè)，主要是倫理上限制。目前發(fā)現(xiàn)好幾個(gè)基因與卵巢癌的發(fā)生有關(guān)，稱(chēng)為“卵巢癌相關(guān)基因”，但這些基因也與其它腫瘤的發(fā)生相關(guān)，并沒(méi)有一個(gè)特異性的卵巢癌基因。在卵巢癌發(fā)生機(jī)理中，更多的是P53基因的突變，但也不是特異性的。目前，技術(shù)上可以把人的全套基因圖譜繪制出來(lái)，但如果大家都去檢測(cè)，會(huì)沖擊社會(huì)倫理底線(xiàn)，還涉及到公民的個(gè)人隱私。這在全世界都是不容許的。
 

7  哪些人需要做輸卵管預(yù)防性切除？

 
由于沒(méi)有特異性的卵巢癌基因，加之舊觀(guān)念的阻礙，針對(duì)任何個(gè)人的輸卵管預(yù)防性切除，都會(huì)引起爭(zhēng)議?，F(xiàn)在的觀(guān)點(diǎn)是，對(duì)于準(zhǔn)備做絕育術(shù)的婦女，可 以用切除輸卵管的辦法代替輸卵管結(jié)扎；對(duì)于做子宮切除術(shù)的婦女，提倡同時(shí)切除雙側(cè)輸卵管。如果家族中有女性成員（如母親、姨媽、姊妹等）患過(guò)乳腺癌或卵巢癌，本人已經(jīng)沒(méi)有生育要求的話(huà)，且年齡等于或超過(guò)了45歲，或者正在進(jìn)行腹部或者下腹部甚至盆腔的手術(shù)，可以要求醫(yī)師預(yù)防性的切除雙側(cè)輸卵管。
 

8  需要切除卵巢嗎，切除輸卵管對(duì)人體有什么危害？

 
卵巢上皮癌的發(fā)生與卵巢本身沒(méi)有多大關(guān)系，所以不需要切除卵巢，當(dāng)然絕經(jīng)后婦女可以考慮將雙側(cè)卵巢切除。輸卵管在人類(lèi)的唯一生理作用是授精和輸送孕卵。一旦沒(méi)有了生育要求，輸卵管就顯得多余。因疾病而切除輸卵管的人很多，還沒(méi)有發(fā)現(xiàn)切除輸卵管對(duì)人體有何危害。對(duì)高危人群而言，個(gè)人建議在45歲以后可切除輸卵管。
 

9  為什么要在45歲之后切除輸卵管？       

 
一是低于這個(gè)年齡的人，或許還有生育要求；二是卵巢上皮癌的發(fā)病年齡較大。當(dāng)然也有年輕患者，但畢竟是少數(shù)。這只是我的個(gè)人觀(guān)點(diǎn)，目前還沒(méi)有學(xué)術(shù)界公認(rèn)的標(biāo)準(zhǔn)。
 

10  切除輸卵管是不是很難？

 
輸卵管切除術(shù)是個(gè)很小的手術(shù)。使用腹腔鏡手術(shù)，是幾分鐘的事情。如果在做其它手術(shù)時(shí)順帶做這個(gè)手術(shù)，是很簡(jiǎn)單的，不提倡專(zhuān)門(mén)到醫(yī)院做輸卵管切除術(shù)。

    相關(guān)閱讀

    孕期食譜推薦

    • 雄起 孕前提高精子質(zhì)量吃啥呦

    • 葉酸買(mǎi)越貴越好嗎？交了智商稅后……

    • 懷孕期間能喝奶茶嗎 懷孕喝奶茶的危害

    • 孕婦食用酸菜魚(yú)的優(yōu)勢(shì) 孕婦食用酸菜魚(yú)注意事項(xiàng)

    熱點(diǎn)推薦

      懷孕期間視頻講座

      編輯推薦

      圖文推薦
      • 女性產(chǎn)后應(yīng)注意哪些事項(xiàng)？

      • 懷孕期間除了補(bǔ)充“葉酸”外，這四種“營(yíng)養(yǎng)”也很重要！看看你們都知道嗎？

      • 懷孕期間，孕媽媽避免做這三件事，也許“黃疸”悄悄“遠(yuǎn)離”寶寶！

      • 懷孕期間多吃這些水果，寶寶出生后不易得黃疸！孕媽媽不要錯(cuò)過(guò)！

      熱點(diǎn)關(guān)注

      Weibo Article 1 Weibo Article 2 Weibo Article 3 Weibo Article 4 Weibo Article 5 Weibo Article 6 Weibo Article 7 Weibo Article 8 Weibo Article 9 Weibo Article 10 Weibo Article 11 Weibo Article 12 Weibo Article 13 Weibo Article 14 Weibo Article 15 Weibo Article 16 Weibo Article 17 Weibo Article 18 Weibo Article 19 Weibo Article 20 Weibo Article 21 Weibo Article 22 Weibo Article 23 Weibo Article 24 Weibo Article 25 Weibo Article 26 Weibo Article 27 Weibo Article 28 Weibo Article 29 Weibo Article 30 Weibo Article 31 Weibo Article 32 Weibo Article 33 Weibo Article 34 Weibo Article 35 Weibo Article 36 Weibo Article 37 Weibo Article 38 Weibo Article 39 Weibo Article 40 Weibo Article 41 Weibo Article 42 Weibo Article 43 Weibo Article 44 Weibo Article 45 Weibo Article 46 Weibo Article 47 Weibo Article 48 Weibo Article 49 Weibo Article 50 Weibo Article 51 Weibo Article 52 Weibo Article 53 Weibo Article 54 Weibo Article 55 Weibo Article 56 Weibo Article 57 Weibo Article 58 Weibo Article 59 Weibo Article 60 Weibo Article 61 Weibo Article 62 Weibo Article 63 Weibo Article 64 Weibo Article 65 Weibo Article 66 Weibo Article 67 Weibo Article 68 Weibo Article 69 Weibo Article 70 Weibo Article 71 Weibo Article 72 Weibo Article 73 Weibo Article 74 Weibo Article 75 Weibo Article 76 Weibo Article 77 Weibo Article 78 Weibo Article 79 Weibo Article 80 Weibo Article 81 Weibo Article 82 Weibo Article 83 Weibo Article 84 Weibo Article 85 Weibo Article 86 Weibo Article 87 Weibo Article 88 Weibo Article 89 Weibo Article 90 Weibo Article 91 Weibo Article 92 Weibo Article 93 Weibo Article 94 Weibo Article 95 Weibo Article 96 Weibo Article 97 Weibo Article 98 Weibo Article 99 Weibo Article 100 Weibo Article 101 Weibo Article 102 Weibo Article 103 Weibo Article 104 Weibo Article 105 Weibo Article 106 Weibo Article 107 Weibo Article 108 Weibo Article 109 Weibo Article 110 Weibo Article 111 Weibo Article 112 Weibo Article 113 Weibo Article 114 Weibo Article 115 Weibo Article 116 Weibo Article 117 Weibo Article 118 Weibo Article 119 Weibo Article 120 Weibo Article 121 Weibo Article 122 Weibo Article 123 Weibo Article 124 Weibo Article 125 Weibo Article 126 Weibo Article 127 Weibo Article 128 Weibo Article 129 Weibo Article 130 Weibo Article 131 Weibo Article 132 Weibo Article 133 Weibo Article 134 Weibo Article 135 Weibo Article 136 Weibo Article 137 Weibo Article 138 Weibo Article 139 Weibo Article 140 Weibo Article 141 Weibo Article 142 Weibo Article 143 Weibo Article 144 Weibo Article 145 Weibo Article 146 Weibo Article 147 Weibo Article 148 Weibo Article 149 Weibo Article 150 Weibo Article 151 Weibo Article 152 Weibo Article 153 Weibo Article 154 Weibo Article 155 Weibo Article 156 Weibo Article 157 Weibo Article 158 Weibo Article 159 Weibo Article 160 Weibo Article 161 Weibo Article 162 Weibo Article 163 Weibo Article 164 Weibo Article 165 Weibo Article 166 Weibo Article 167 Weibo Article 168 Weibo Article 169 Weibo Article 170 Weibo Article 171 Weibo Article 172 Weibo Article 173 Weibo Article 174 Weibo Article 175 Weibo Article 176 Weibo Article 177 Weibo Article 178 Weibo Article 179 Weibo Article 180 Weibo Article 181 Weibo Article 182 Weibo Article 183 Weibo Article 184 Weibo Article 185 Weibo Article 186 Weibo Article 187 Weibo Article 188 Weibo Article 189 Weibo Article 190 Weibo Article 191 Weibo Article 192 Weibo Article 193 Weibo Article 194 Weibo Article 195 Weibo Article 196 Weibo Article 197 Weibo Article 198 Weibo Article 199 Weibo Article 200 Weibo Article 201 Weibo Article 202 Weibo Article 203 Weibo Article 204 Weibo Article 205 Weibo Article 206 Weibo Article 207 Weibo Article 208 Weibo Article 209 Weibo Article 210 Weibo Article 211 Weibo Article 212 Weibo Article 213 Weibo Article 214 Weibo Article 215 Weibo Article 216 Weibo Article 217 Weibo Article 218 Weibo Article 219 Weibo Article 220 Weibo Article 221 Weibo Article 222 Weibo Article 223 Weibo Article 224 Weibo Article 225 Weibo Article 226 Weibo Article 227 Weibo Article 228 Weibo Article 229 Weibo Article 230 Weibo Article 231 Weibo Article 232 Weibo Article 233 Weibo Article 234 Weibo Article 235 Weibo Article 236 Weibo Article 237 Weibo Article 238 Weibo Article 239 Weibo Article 240 Weibo Article 241 Weibo Article 242 Weibo Article 243 Weibo Article 244 Weibo Article 245 Weibo Article 246 Weibo Article 247 Weibo Article 248 Weibo Article 249 Weibo Article 250 Weibo Article 251 Weibo Article 252 Weibo Article 253 Weibo Article 254 Weibo Article 255 Weibo Article 256 Weibo Article 257 Weibo Article 258 Weibo Article 259 Weibo Article 260 Weibo Article 261 Weibo Article 262 Weibo Article 263 Weibo Article 264 Weibo Article 265 Weibo Article 266 Weibo Article 267 Weibo Article 268 Weibo Article 269 Weibo Article 270 Weibo Article 271 Weibo Article 272 Weibo Article 273 Weibo Article 274 Weibo Article 275 Weibo Article 276 Weibo Article 277 Weibo Article 278 Weibo Article 279 Weibo Article 280 Weibo Article 281 Weibo Article 282 Weibo Article 283 Weibo Article 284 Weibo Article 285 Weibo Article 286 Weibo Article 287 Weibo Article 288 Weibo Article 289 Weibo Article 290 Weibo Article 291 Weibo Article 292 Weibo Article 293 Weibo Article 294 Weibo Article 295 Weibo Article 296 Weibo Article 297 Weibo Article 298 Weibo Article 299 Weibo Article 300 Weibo Article 301 Weibo Article 302 Weibo Article 303 Weibo Article 304 Weibo Article 305 Weibo Article 306 Weibo Article 307 Weibo Article 308 Weibo Article 309 Weibo Article 310 Weibo Article 311 Weibo Article 312 Weibo Article 313 Weibo Article 314 Weibo Article 315 Weibo Article 316 Weibo Article 317 Weibo Article 318 Weibo Article 319 Weibo Article 320 Weibo Article 321 Weibo Article 322 Weibo Article 323 Weibo Article 324 Weibo Article 325 Weibo Article 326 Weibo Article 327 Weibo Article 328 Weibo Article 329 Weibo Article 330 Weibo Article 331 Weibo Article 332 Weibo Article 333 Weibo Article 334 Weibo Article 335 Weibo Article 336 Weibo Article 337 Weibo Article 338 Weibo Article 339 Weibo Article 340 Weibo Article 341 Weibo Article 342 Weibo Article 343 Weibo Article 344 Weibo Article 345 Weibo Article 346 Weibo Article 347 Weibo Article 348 Weibo Article 349 Weibo Article 350 Weibo Article 351 Weibo Article 352 Weibo Article 353 Weibo Article 354 Weibo Article 355 Weibo Article 356 Weibo Article 357 Weibo Article 358 Weibo Article 359 Weibo Article 360 Weibo Article 361 Weibo Article 362 Weibo Article 363 Weibo Article 364 Weibo Article 365 Weibo Article 366 Weibo Article 367 Weibo Article 368 Weibo Article 369 Weibo Article 370 Weibo Article 371 Weibo Article 372 Weibo Article 373 Weibo Article 374 Weibo Article 375 Weibo Article 376 Weibo Article 377 Weibo Article 378 Weibo Article 379 Weibo Article 380 Weibo Article 381 Weibo Article 382 Weibo Article 383 Weibo Article 384 Weibo Article 385 Weibo Article 386 Weibo Article 387 Weibo Article 388 Weibo Article 389 Weibo Article 390 Weibo Article 391 Weibo Article 392 Weibo Article 393 Weibo Article 394 Weibo Article 395 Weibo Article 396 Weibo Article 397 Weibo Article 398 Weibo Article 399 Weibo Article 400 Weibo Article 401 Weibo Article 402 Weibo Article 403 Weibo Article 404 Weibo Article 405 Weibo Article 406 Weibo Article 407 Weibo Article 408 Weibo Article 409 Weibo Article 410 Weibo Article 411 Weibo Article 412 Weibo Article 413 Weibo Article 414 Weibo Article 415 Weibo Article 416 Weibo Article 417 Weibo Article 418 Weibo Article 419 Weibo Article 420 Weibo Article 421 Weibo Article 422 Weibo Article 423 Weibo Article 424 Weibo Article 425 Weibo Article 426 Weibo Article 427 Weibo Article 428 Weibo Article 429 Weibo Article 430 Weibo Article 431 Weibo Article 432 Weibo Article 433 Weibo Article 434 Weibo Article 435 Weibo Article 436 Weibo Article 437 Weibo Article 438 Weibo Article 439 Weibo Article 440 Weibo Article 441 Weibo Article 442 Weibo Article 443 Weibo Article 444 Weibo Article 445 Weibo Article 446 Weibo Article 447 Weibo Article 448 Weibo Article 449 Weibo Article 450 Weibo Article 451 Weibo Article 452 Weibo Article 453 Weibo Article 454 Weibo Article 455 Weibo Article 456 Weibo Article 457 Weibo Article 458 Weibo Article 459 Weibo Article 460 Weibo Article 461 Weibo Article 462 Weibo Article 463 Weibo Article 464 Weibo Article 465 Weibo Article 466 Weibo Article 467 Weibo Article 468 Weibo Article 469 Weibo Article 470 Weibo Article 471 Weibo Article 472 Weibo Article 473 Weibo Article 474 Weibo Article 475 Weibo Article 476 Weibo Article 477 Weibo Article 478 Weibo Article 479 Weibo Article 480 Weibo Article 481 Weibo Article 482 Weibo Article 483 Weibo Article 484 Weibo Article 485 Weibo Article 486 Weibo Article 487 Weibo Article 488 Weibo Article 489 Weibo Article 490 Weibo Article 491 Weibo Article 492 Weibo Article 493 Weibo Article 494 Weibo Article 495 Weibo Article 496 Weibo Article 497 Weibo Article 498 Weibo Article 499 Weibo Article 500 Weibo Article 501 Weibo Article 502 Weibo Article 503 Weibo Article 504 Weibo Article 505 Weibo Article 506 Weibo Article 507 Weibo Article 508 Weibo Article 509 Weibo Article 510 Weibo Article 511 Weibo Article 512 Weibo Article 513 Weibo Article 514 Weibo Article 515 Weibo Article 516 Weibo Article 517 Weibo Article 518 Weibo Article 519 Weibo Article 520 Weibo Article 521 Weibo Article 522 Weibo Article 523 Weibo Article 524 Weibo Article 525 Weibo Article 526 Weibo Article 527 Weibo Article 528 Weibo Article 529 Weibo Article 530 Weibo Article 531 Weibo Article 532 Weibo Article 533 Weibo Article 534 Weibo Article 535 Weibo Article 536 Weibo Article 537 Weibo Article 538 Weibo Article 539 Weibo Article 540 Weibo Article 541 Weibo Article 542 Weibo Article 543 Weibo Article 544 Weibo Article 545 Weibo Article 546 Weibo Article 547 Weibo Article 548 Weibo Article 549 Weibo Article 550 Weibo Article 551 Weibo Article 552 Weibo Article 553 Weibo Article 554 Weibo Article 555 Weibo Article 556 Weibo Article 557 Weibo Article 558 Weibo Article 559 Weibo Article 560 Weibo Article 561 Weibo Article 562 Weibo Article 563 Weibo Article 564 Weibo Article 565 Weibo Article 566 Weibo Article 567 Weibo Article 568 Weibo Article 569 Weibo Article 570 Weibo Article 571 Weibo Article 572 Weibo Article 573 Weibo Article 574 Weibo Article 575 Weibo Article 576 Weibo Article 577 Weibo Article 578 Weibo Article 579 Weibo Article 580 Weibo Article 581 Weibo Article 582 Weibo Article 583 Weibo Article 584 Weibo Article 585 Weibo Article 586 Weibo Article 587 Weibo Article 588 Weibo Article 589 Weibo Article 590 Weibo Article 591 Weibo Article 592 Weibo Article 593 Weibo Article 594 Weibo Article 595 Weibo Article 596 Weibo Article 597 Weibo Article 598 Weibo Article 599 Weibo Article 600 Weibo Article 601 Weibo Article 602 Weibo Article 603 Weibo Article 604 Weibo Article 605 Weibo Article 606 Weibo Article 607 Weibo Article 608 Weibo Article 609 Weibo Article 610 Weibo Article 611 Weibo Article 612 Weibo Article 613 Weibo Article 614 Weibo Article 615 Weibo Article 616 Weibo Article 617 Weibo Article 618 Weibo Article 619 Weibo Article 620 Weibo Article 621 Weibo Article 622 Weibo Article 623 Weibo Article 624 Weibo Article 625 Weibo Article 626 Weibo Article 627 Weibo Article 628 Weibo Article 629 Weibo Article 630 Weibo Article 631 Weibo Article 632 Weibo Article 633 Weibo Article 634 Weibo Article 635 Weibo Article 636 Weibo Article 637 Weibo Article 638 Weibo Article 639 Weibo Article 640 Weibo Article 641 Weibo Article 642 Weibo Article 643 Weibo Article 644 Weibo Article 645 Weibo Article 646 Weibo Article 647 Weibo Article 648 Weibo Article 649 Weibo Article 650 Weibo Article 651 Weibo Article 652 Weibo Article 653 Weibo Article 654 Weibo Article 655 Weibo Article 656 Weibo Article 657 Weibo Article 658 Weibo Article 659 Weibo Article 660 Weibo Article 661 Weibo Article 662 Weibo Article 663 Weibo Article 664 Weibo Article 665 Weibo Article 666 Weibo Article 667 Weibo Article 668 Weibo Article 669 Weibo Article 670 Weibo Article 671 Weibo Article 672 Weibo Article 673 Weibo Article 674 Weibo Article 675 Weibo Article 676 Weibo Article 677 Weibo Article 678 Weibo Article 679 Weibo Article 680 Weibo Article 681 Weibo Article 682 Weibo Article 683 Weibo Article 684 Weibo Article 685 Weibo Article 686 Weibo Article 687 Weibo Article 688 Weibo Article 689 Weibo Article 690 Weibo Article 691 Weibo Article 692 Weibo Article 693 Weibo Article 694 Weibo Article 695 Weibo Article 696 Weibo Article 697 Weibo Article 698 Weibo Article 699 Weibo Article 700 Weibo Article 701 Weibo Article 702 Weibo Article 703 Weibo Article 704 Weibo Article 705 Weibo Article 706 Weibo Article 707 Weibo Article 708 Weibo Article 709 Weibo Article 710 Weibo Article 711 Weibo Article 712 Weibo Article 713 Weibo Article 714 Weibo Article 715 Weibo Article 716 Weibo Article 717 Weibo Article 718 Weibo Article 719 Weibo Article 720 Weibo Article 721 Weibo Article 722 Weibo Article 723 Weibo Article 724 Weibo Article 725 Weibo Article 726